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RICE MORPHOLOGY DETERMINANT Encodes the Type II Formin FH5 and Regulates Rice Morphogenesis.

Plant Cell. 2011 Feb 9;

Authors: Zhang Z, Zhang Y, Tan H, Wang Y, Li G, Liang W, Yuan Z, Hu J, Ren H, Zhang D

Multicellular organisms contain a large number of formins; however, their physiological roles in plants remain poorly understood. Here, we reveal that formin homology 5 (FH5), a type II formin mutated in rice morphology determinant (rmd), plays a crucial role in determining rice (Oryza sativa) morphology. FH5/RMD encodes a formin-like protein consisting of an N-terminal phosphatase tensin (PTEN)-like domain, an FH1 domain, and an FH2 domain. The rmd mutants display a bending growth pattern in seedlings, are stunted as adult plants, and have aberrant inflorescence (panicle) and seed shape. Cytological analysis showed that rmd mutants have severe cell elongation defects and abnormal microtubule and microfilament arrays. FH5/RMD is ubiquitously expressed in rice tissues, and its protein localization to the chloroplast surface is mediated by the PTEN domain. Biochemical assays demonstrated that recombinant FH5 protein can nucleate actin polymerization from monomeric G-actin or actin/profilin complexes, cap the barbed end of actin filaments, and bundle actin filaments in vitro. Moreover, FH5 can directly bind to and bundle microtubules through its FH2 domain in vitro. Our findings suggest that the rice formin protein FH5 plays a critical role in determining plant morphology by regulating actin dynamics and proper spatial organization of microtubules and microfilaments.

已有 9 条评论

  1. 恭喜!
    一眼看去全是Zhang啊

  2. @azalea 大姓啊~ 三个主人公倒都是zhang, 呵呵

  3. shane shane

    恭喜恭喜~~~

  4. makun makun

    坚持坚持,加油加油

  5. makun makun

    你好,我的毕业外文翻译是翻译这篇论文,可是,遇到了一些困难,想请教一下,能不能告诉我下,这个题目中的the Type IIFormin FH5是什么意思呢?查了好多都不能确定具体的意思。如果可以的话,可不可以把整个题目的意思告诉我下!谢谢!谢谢!

  6. molezz molezz

    @makun formin家族水稻21个成员, 5是其中一个, formin分2类, typeI和typeII, II一般有PTEN, I有跨膜功能域, 具体可以看这方面的综述2004

  7. makun makun

    @molezz
    嗯,谢谢您。我也看了一些关于您的这篇论文的报导,我现在把题目翻译为水稻形态的决定子编码了一个二型formin蛋白FH5来控制水稻形态的发生,不知道这样翻译行不行?还是说控制水稻形态的基因编码了一个二型formin蛋白FH5来控制水稻形态的发生这样更好些呢?因为我只是农学专业的,所以分子生物学这方面了解的不是很多,大多数还是我在网上查到的,对于这个还希望您给一些好的建议,呵呵。这方面的综述我也会再看看的,以后遇到问题可能还会麻烦您,所以先在这谢谢您了!!!

  8. molezz molezz

    后面那个说法对 RICE MORPHOLOGY DETERMINANT这里斜体表示突变体株

  9. makun makun
    molezz :后面那个说法对 RICE MORPHOLOGY DETERMINANT这里斜体表示突变体株

    噢,原来是这个意思,谢谢您的帮助!麻烦您了!

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